Publications

An Endogenous Retrovirus Vaccine Encoding an Envelope with a Mutated Immunosuppressive Domain in Combination with Anti-PD1 Treatment Eradicates Established Tumours in Mice. Viruses.

Daradoumis J, Ragonnaud E, Skandorff I, Nielsen KN, Bermejo AV, Andersson AM, Schroedel S, Thirion C, Neukirch L, Holst PJ. 2023 Apr 6;15(4):926. doi: 10.3390/v15040926. PMID: 37112906; PMCID: PMC10141008.

Efficacy and Synergy with Cisplatin of an Adenovirus Vectored Therapeutic E1E2E6E7 Vaccine against HPV Genome-Positive C3 Cancers in Mice. Cancer Immunol Res.

2023 Feb 3;11(2):261-275. doi: 10.1158/2326-6066.CIR-22-0174. PMID: 36534088.

Immunogenicity of Human Endogenous Retroviral Proteins in Cancer and Discussion of Therapeutic Approaches.

Int J Mol Sci. 2022 Jan 25;23(3):1330. doi: 10.3390/ijms23031330. PMID: 35163254; PMCID: PMC8836156.

Novel Antigenic Targets of HPV Therapeutic Vaccines. Vaccines (Basel)

Boilesen DR, Nielsen KN, Holst PJ. . 2021 Nov 1;9(11):1262. doi: 10.3390/vaccines9111262. PMID: 34835193; PMCID: PMC8621534.

Design and Immunological Validation of Macaca fascicularis Papillomavirus Type 3 Based Vaccine Candidates in Outbred Mice: Basis for Future Testing of a Therapeutic Papillomavirus Vaccine in NHPs. Front Immunol.

Neckermann P, Boilesen DR, Willert T, Pertl C, Schrödel S, Thirion C, Asbach B, Holst PJ, Wagner R. 2021 Oct 28;12:761214. doi: 10.3389/fimmu.2021.761214. PMID: 34777375; PMCID: PMC8581358.

MHC class II invariant chain-adjuvanted viral vectored vaccines enhances T cell responses in humans.

Esposito I, Cicconi P, D’Alise AM, Brown A, Esposito M, Swadling L, Holst PJ, Bassi MR, Stornaiuolo M, Mori F, Vassilev V, Li W, Donnison T, Gentile C, Turner B, von Delft A, Del Sorbo M, Barra F, Contino AM, Abbate A, Novellino E, Thomsen AR, Christensen JP, Lahm A, Grazioli F, Ammendola V, Siani L, Colloca S, Klenerman P, Nicosia A, Dorrell L, Folgori A, Capone S, Barnes E; PEACHI Consortium. Sci Transl Med. 2020 Jun 17;12(548):eaaz7715. doi: 10.1126/scitranslmed.aaz7715. PMID: 32554708; PMCID: PMC7610808.

The potential of adenoviral vaccine vectors with altered antigen presentation capabilities. Expert Rev Vaccines

Neukirch L, Fougeroux C, Andersson AC, Holst PJ. 2020 Jan;19(1):25-41. doi: 10.1080/14760584.2020.1711054. Epub 2020 Jan 23. PMID: 31889453.

Cancer Associated Endogenous Retroviruses: Ideal Immune Targets for Adenovirus-Based Immunotherapy.

Bermejo, AV; Ragonnaud, E; Daradoumis J; Holst, PJ. Int. J. Mol. Sci. 2020, 21(14), 4843

Adenovirus based virus-like-vaccines targeting endogenous retroviruses can eliminate growing colorectal cancers in mice.

Neukirch, L.; Nielsen, T. K.; Laursen, H.; Daradoumis, J.; Thirion, C.; Holst, P. J.
Oncotarget, 02, 2019, Vol. 10, 1458-1472.

Replication deficient human adenovirus vector serotype 19a/64: Immunogenicity in mice and female cynomolgus macaques.

Ragonnaud, E.; Schroedel, S.; Mariya, S.; Iskandriati, D.; Pamungkas, J.; Fougeroux, C.; Daradoumis, J.; Thomsen, A. R.; Neukirch, L.; Ruzsics, Z.; Salomon, M.; Thirion, C.; Holst P. J.
Vaccine, 10, 2018, Vol. 36(41), 6212–6222.

Virus-Like-Vaccines against HIV.

Andersson A. M. C.; Schwerdtfeger, M.; Holst, P. J. Vaccines, 01, 2018, Vol. 6(1), 10.

Mucosal Vaccination with Heterologous Viral Vectored Vaccine Targeting Subdominant SIV Accessory Antigens Strongly Inhibits Early Viral Replication.

Xu, H.; Andersson, A. M.; Ragonnaud, E.; Boilesen, D.; Tolver, A.; Jensen, B. A. H.; Blanchard, J. L.; Nicosia, A.; Folgori, A.; Colloca, S.; Cortese, R.; Thomsen, A. R.; Christensen, J. P.; Veazey, R. S.; Holst, P. J.
EBioMedicine, 04, 2017, Vol. 18, 204-215.

Novel adenovirus encoded virus-like particles displaying the placental malaria associated VAR2CSA antigen.

Andersson, A.M. C.; Resende, M.; Salanti, A.; Nielsen, M. A.; Holst, P. J.
Vaccine, 02, 2017, Vol. 35(8), 1140–1147.

Therapeutic Vaccine Against Primate Papillomavirus Infections of the Cervix.

Ragonnaud, E.; Andersson, A. M. C.; Mariya, S.; Pedersen, A. G.; Burk, R. D.; Folgori, A.; Colloca, S.; Cortese, R.; Nicosia, A.; Pamungkas, J.; Iskandriati, D.; Holst, P. J.
Journal of Immunotherapy, 02, 2017, Vol. 40(2), 51-61.

Increased T cell breadth and antibody response elicited in prime-boost regimen by viral vector encoded homologous SIV Gag/Env in outbred CD1 mice.

Andersson, A. M. C.; Holst, P. J.
Journal of Translational Medicine, 12, 2016, Vol. 14(1), 343.

Effect of HIV-1 envelope cytoplasmic tail on adenovirus primed virus encoded virus-like particle immunizations.

Xu, H.; Andersson, A. M. C.; Ragonnaud, E.; Seaton, K. E.; Sawant, S.; Folgori, A., Colloca, S.; Labranche, S.; Montefiori, D. C.; Tomaras, G. D.; Holst, P. J.
Vaccine, 10, 2016, Vol. 34(44), 5344-5351.

Oncofetal Chondroitin Sulfate Glycosaminoglycans Are Key Players in Integrin Signaling and Tumor Cell Motility.

Clausen, T. M.; Pereira, M. A.; Nakouzi, N. A.; Oo, H. Z.; Agerbæk, M. Ø.; Lee, S.; Ørum-Madsen, M. S.; Kristensen, A. R.; El-Naggerm A.; Grandgenett, P. M.; Grem, J. L.; Hollingsworth, M. A.; Holst, P. J.; Theander, T.; Sorensen, P. H.; Daugaard, M.; Salanti, A.
Molecular Cancer Research, 09, 2016, Vol. 14(12), 1288-1299.